Minimap2 is a versatile sequence alignment program that aligns DNA or mRNA sequences against a large reference database. Typical use cases include: (1) mapping PacBio or Oxford Nanopore genomic reads to the human genome; (2) finding overlaps between long reads with error rate up to ~15%; (3) splice-aware alignment of PacBio Iso-Seq or Nanopore cDNA or Direct RNA reads against a reference genome; (4) aligning Illumina single- or paired-end reads; (5) assembly-to-assembly alignment; (6) full-genome alignment between two closely related species with divergence below ~15%. For ~10kb noisy reads sequences, minimap2 is tens of times faster than mainstream long-read mappers such as BLASR, BWA-MEM, NGMLR and GMAP. It is more accurate on simulated long reads and produces biologically meaningful alignment ready for downstream analyses. For >100bp Illumina short reads, minimap2 is three times as fast as BWA-MEM and Bowtie2, and as accurate on simulated data. Detailed evaluations are available from the minimap2 paper (https://doi.org/10.1093/bioinformatics/bty191).
OS | Architecture | Version |
---|---|---|
NetBSD 10.0 | i386 | minimap2-2.28nb1.tgz |
NetBSD 10.0 | i386 | minimap2-2.24nb1.tgz |
NetBSD 10.0 | i386 | minimap2-2.27.tgz |
NetBSD 10.0 | i386 | minimap2-2.28nb1.tgz |
NetBSD 10.0 | x86_64 | minimap2-2.28nb1.tgz |
NetBSD 10.0 | x86_64 | minimap2-2.24nb1.tgz |
NetBSD 10.0 | x86_64 | minimap2-2.27.tgz |
NetBSD 10.0 | x86_64 | minimap2-2.28nb1.tgz |
NetBSD 9.0 | i386 | minimap2-2.28nb1.tgz |
NetBSD 9.0 | i386 | minimap2-2.24nb1.tgz |
NetBSD 9.0 | i386 | minimap2-2.27.tgz |
NetBSD 9.0 | i386 | minimap2-2.28nb1.tgz |
NetBSD 9.0 | x86_64 | minimap2-2.28nb1.tgz |
NetBSD 9.0 | x86_64 | minimap2-2.24nb1.tgz |
NetBSD 9.0 | x86_64 | minimap2-2.27.tgz |
NetBSD 9.0 | x86_64 | minimap2-2.28nb1.tgz |
NetBSD 9.3 | x86_64 | minimap2-2.28nb1.tgz |
NetBSD 9.3 | x86_64 | minimap2-2.28nb1.tgz |
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